Indexing
CÁC SỐ TỪ 2011-2023
Tạp chí Y Dược Học
Abstract
Background-Objectives: The administration of antibiotics in patients undergoing laparoscopic appendectomy remains a matter of concern. This study aimed to evaluate the outcomes of a single-dose prophylactic antibiotic regimen in laparoscopic surgery for acute uncomplicated appendicitis.
Materials and Methods: This prospective study included 414 patients with non-perforated appendicitis who underwent laparoscopic appendectomy at Hue University of Medicine and Pharmacy Hospital from January 2022 to December 2023. Among them, 207 patients in Group 1 received a single dose of prophylactic antibiotics, while 207 patients in Group 2 received postoperative antibiotics.
Results: There were no statistically significant differences between the two groups in terms of demographic and clinical characteristics. The mean operative time was 29.5 ± 6.1 minutes in Group 1 compared to 29.3 ± 6.0 minutes in Group 2 (p > 0.05). The time to bowel motility recovery after surgery was 12.8 ± 3.8 hours in Group 1 and 12.6 ± 2.4 hours in Group 2 (p > 0.05). Postoperative complications occurred in 5.3% of patients in Group 1 and 6.3% in Group 2 (p > 0.05). The duration of analgesic use, intravenous antibiotic treatment, and postoperative hospitalization were significantly shorter in Group 1 (1.1 ± 0.4 days, 0.2 ± 1.1 days, and 2.5 ± 1.0 days, respectively) compared to Group 2 (1.4 ± 0.5 days, 3.0 ± 1.0 days, and 3.5 ± 1.0 days, respectively) (p < 0.05).
Conclusion: A single-dose prophylactic antibiotic regimen is sufficient for laparoscopic surgery in patients with acute uncomplicated appendicitis.
| Published | 2026-03-30 | |
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| Issue | Vol. 16 No. 1 (2026) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2026.1.1026 | |
| Keywords | Kháng sinh dự phòng, kháng sinh dự phòng một liều duy nhất, phẫu thuật nội soi, viêm ruột thừa cấp chưa biến chứng Prophylactic antibiotics, single-dose prophylactic antibiotics, laparoscopy, acute uncomplicated appendicitis |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2026 Hue Journal of Medicine and Pharmacy
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