Abstract
Malignant biliary obstruction is common, yet severe, clinical condition caused by various etiologies such as cholangiocarcinoma, pancreatic cancer, hepatocellular carcinoma, metastatic lymphadenopathy… Histopathological confirmation of the nature of the biliary stricture is requisite for oncologic therapies. Percutaneous transluminal forceps biopsy (PTFB) is a safe and effective alternative to traditional endoscopic retrograde cholangiopancreatography-guided brushing, cyto-aspiration or biopsy, endoscopic ultrasound
guided fine-needle aspiration or percutaneous transabdominal biopsy in cases where the lesions are deemed unfeasible or potentially high risk for the aforementioned modalities. We report 3 cases of obstructive jaundice compatible with malignant biliary obstruction based on clinical presentation, laboratory tests and imaging findings. These patients underwent PTFB combined with percutaneous transhepatic biliary drainage for the management of obstruction. All the samples were pathologically diagnostic as malignant. PTFB is a safe and effective procedure for tissue sampling which facilitate further oncologic treatments.
| Published | 2026-03-28 | |
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| Issue | Vol. 16 No. 1 (2026) | |
| Section | Original Articles | |
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| Keywords | vàng da, mật, u, sinh thiết, dẫn lưu jaundice, bile, neoplasms, biopsy, drainage |

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