Abstract
Objectives: (1) To characterize the clinical, endoscopic, and histopathological features of colorectal polyps ≥ 20 mm; (2) To evaluate the efficacy and safety of prophylactic clipping in endoscopic resection of these lesions.
Methods: An observational study was conducted on 63 patients (67 polyps ≥ 20 mm) at Family Hospital Da Nang (March 2024 – September 2025). Resection techniques included hot snare polypectomy (HSP), conventional endoscopic mucosal resection (CEMR), and stalked endoscopic mucosal resection (S-EMR). All resection sites underwent mandatory prophylactic clip closure. Outcomes included en bloc resection rates, immediate/delayed complications, and 3-month follow-up findings.
Results: The majority of patients were male (55.6%) and aged ≥ 40 years (77.8%). Polyps were predominantly located in the sigmoid colon (38.8%) and rectum (22.4%). The overall en bloc resection rate was 83.6%, with HSP achieving the highest success (92.5%, p = 0.01). A total of 119 clips were applied (mean: 1.8 ± 1.2 per polyp). Notably, the incidence of DPPB was 0%. Immediate complications (bleeding 3.2%, perforation 1.6%) were successfully managed endoscopically. At 3 months, the residual/recurrence rate was 3.2%, and 6.3% of patients had retained clips.
Conclusions: Prophylactic clipping following the resection of large colorectal polyps (≥ 20 mm) is a safe and highly effective strategy for preventing DPPB and managing immediate complications.
| Published | 2026-09-28 | |
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| Issue | Vol. 16 No. 5 (2026) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2026.5.1057 | |
| Keywords | Colorectal polyps, endoscopic polypectomy, prophylactic clip closure, delayed post-polypectomy bleeding Polyp đại trực tràng, cắt polyp qua nội soi, kẹp clip dự phòng, chảy máu muộn sau cắt polyp |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2026 Hue Journal of Medicine and Pharmacy
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