Abstract
Background: Lower urinary tract symptoms are very common in older men and affect patients’ quality of life as well as increase medical costs, most often caused by benign prostatic hyperplasia. One of the consequences of benign prostatic hyperplasia is the bladder outlet obstruction, causing lower urinary tract symptoms (LUTS) and affecting the urinary flow rate; affecting the detrusor muscle, increased post void residual urine (PVR). Objectives: To investigate the clinical characteristics and correlation between the severity of symptoms according to IPSS with some factors such as urinary flow rate, prostate volume, intravesical prostatic protrusion (IPP), post void residual urine (PVR); correlation between prostate volume and urinary flow rate in patients of benign prostatic hyperplasia with lower urinary tract symptoms. Materials and methods: A cross-sectional descriptive study in 97 patients of benign prostatic hyperplasia with lower urinary tract symptoms who came to the Hospital of Hue University of Medicine and Pharmacy from September 2022 to March 2023. All patients in the study were surveyed about clinical symptoms, assessed the severity of symptoms according to IPSS, some suprapubic ultrasound characteristics of the prostate gland and uroflowmetry. At the same time, evaluate the correlation between the IPSS with a number of factors such as urinary flow rate, prostate volume, intravesical prostatic protrusion, post voiding residual urine; correlation between prostate volume on ultrasound and urinary flow rate. Results: The most common group of lower urinary tract symptoms was the voiding symptoms (97.9%), the group of storage and postmicturition symptoms also accounted for a high proportion (96.9% and 86.6%). The majority of patients had symptoms of all three symptom groups (82.5%). The most common symptom is weak urine stream (85.6%). Most of the patients had moderate (52.6%) and severe (42.3%). The mean IPSS was 17.4 ± 5.2 and the QoL was 3.9 ± 1.0. There was a negative correlation between IPSS and maximum flow rate Qmax (r = -0.535, p < 0.05), and average flow rate Qave (r = -0.488, p < 0.05). There was a positive correlation between IPSS with intravesical prostatic protrusion (r = 0.381; p < 0.05) and post voiding residual urine volume PVR (r = 0.397; p < 0.05). There was no correlation between prostate volume and maximum flow rate Qmax (r = -0.067, p > 0.05) and average flow rate Qave (r = -0.135, p>0.05). Conclusion: Urinary weakness and voiding symptoms were the most common in patients with benign prostatic hyperplasia. The majority of patients have moderate to severe symptoms. There is a negative correlation between IPSS with maximum urinary flow rate and average urinary flow rate. There is a positive correlation between IPSS with intravesical prostatic protrusion and post void residual urinary volume. There is no correlation between prostate volume and maximum flow rate and mean flow rate.
| Published | 2025-06-25 | |
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| Issue | Vol. 15 No. 3 (2025) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2025.3.27 | |
| Keywords | triệu chứng đường tiểu dưới, tăng sinh lành tính tuyến tiền liệt, IPSS, tốc độ dòng tiểu, thể tích tuyến tiền liệt benign prostatic hyperplasia, lower urinary tract symptoms, international prostate symptom score IPSS, uroflow rate, prostate volume, intravesical prostatic protrusion (IPP), post void residual urine (PVR) |
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Copyright (c) 2025 Hue Journal of Medicine and Pharmacy
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