Abstract
Background: Secondary osteoporosis in hemodialysis patients is a common metabolic complication. This study aims to investigate bone mineral density, osteoporosis, and factors related to bone mineral density (BMD) and osteoporosis in hemodialysis patients. Methods: This is a cross-sectional descriptive study; the study subjects included 84 patients undergoing hemodialysis at the Hemodialysis and Nephrology Departments, Hue Central Hospital, from May 2023 to May 2025. Results: The mean BMD values were 1.073 ± 0.217 g/cm² at the lumbar spine, 0.877 ± 0.184 g/cm² at the total hip, and 0.819 ± 0.184 g/cm² at the hip neck. According to WHO diagnostic criteria. 20.20% of patients had osteoporosis and 32.10% had osteopenia. Multivariate regression analysis of bone mineral density in the total hip and lumbar spine was found to be related to age, BMI, and blood PTH; multivariate regression analysis, bone mineral density in the hip neck was associated with age, gender, BMI, and blood PTH. Multivariable logistic regression showed that osteoporosis risk was associated with age and elevated blood PTH levels. Conclusions: The prevalence of osteoporosis and osteopenia was relatively high among maintenance hemodialysis patients. BMD and osteoporosis in hemodialysis patients were significantly associated with age, gender, and blood PTH levels.
| Published | 2026-03-30 | |
| Fulltext |
|
|
| Language |
|
|
| Issue | Vol. 16 No. 1 (2026) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2026.1.810 | |
| Keywords |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2026 Hue Journal of Medicine and Pharmacy
Kovesdy CP. Epidemiology of chronic kidney disease: an update 2022. Kidney Int Suppl (2020). 2022;12:7–11.
Bello AK, Okpechi IG, Osman MA, Cho Y, Htay H, Jha V, et al. Epidemiology of haemodialysis outcomes. Nat Rev Nephrol. 2022;18(6):378–95.
Kidney Disease: Improving Global Outcomes (KDIGO). KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of CKD–MBD. Kidney Int Suppl (2011). 2017;7(1):1–59.
Kanis JA, Melton LJ, Christiansen C, Johnston CC, Khaltaev N. The diagnosis of osteoporosis. J Bone Miner Res. 1994;9(8):1137–41
Nguyễn Thanh Minh, Nghiên cứu rối loạn xương, khoáng và các yếu tố liên quan trên bệnh nhân bệnh thận mạn giai đoạn 5 lọc máu chu kỳ ,Luận án Tiến sĩ, Trường Đại học Y Dược Huế; 2021.
Nhớ BT, Châu TTT, Hà ĐTV. Khảo sát mật độ xương và các yếu tố liên quan ở bệnh nhân suy thận mạn tại Bệnh viện 19-8. Tạp chí Y học Việt Nam. 2023;527(1B):59–65.
Hashimoto H, Shikuma S, Mandai S, Adachi S, Uchida S. Calcium-based phosphate binder use is associated with lower risk of osteoporosis in hemodialysis patients. Sci Rep. 2021;11(1):1924.
Amirkhanlou S, Roshandel G, Aghaei M, Mohebi H, Tabatabei SS, Momen S, et al. Assessment of bone mineral density in patients undergoing hemodialysis: an Iranian population-based study. Arch Iran Med. 2021;24(8):611–8.
Nguyễn Thị Dững, Võ Tam, Loãng xương và các yếu tố nguy cơ ở bệnh nhân lọc máu định kỳ. Tạp chí Y Dược học – Trường Đại học Y Dược Huế. 2024;24:45–52.
Slouma M, Sahli H, Bahlous A, Laadhar L, Smaoui W, Rekik S, et al. Mineral bone disorder and osteoporosis in hemodialysis patients. Adv Rheumatol. 2020;60(1):26–33
Kovesdy CP. Epidemiology of chronic kidney disease: an update 2022. Kidney Int Suppl (2020). 2022;12:7–11.
Bello AK, Okpechi IG, Osman MA, Cho Y, Htay H, Jha V, et al. Epidemiology of haemodialysis outcomes. Nat Rev Nephrol. 2022;18(6):378–95.
Kidney Disease: Improving Global Outcomes (KDIGO). KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of CKD–MBD. Kidney Int Suppl (2011). 2017;7(1):1–59.
Kanis JA, Melton LJ, Christiansen C, Johnston CC, Khaltaev N. The diagnosis of osteoporosis. J Bone Miner Res. 1994;9(8):1137–41
Nguyễn Thanh Minh, Nghiên cứu rối loạn xương, khoáng và các yếu tố liên quan trên bệnh nhân bệnh thận mạn giai đoạn 5 lọc máu chu kỳ ,Luận án Tiến sĩ, Trường Đại học Y Dược Huế; 2021.
Nhớ BT, Châu TTT, Hà ĐTV. Khảo sát mật độ xương và các yếu tố liên quan ở bệnh nhân suy thận mạn tại Bệnh viện 19-8. Tạp chí Y học Việt Nam. 2023;527(1B):59–65.
Hashimoto H, Shikuma S, Mandai S, Adachi S, Uchida S. Calcium-based phosphate binder use is associated with lower risk of osteoporosis in hemodialysis patients. Sci Rep. 2021;11(1):1924.
Amirkhanlou S, Roshandel G, Aghaei M, Mohebi H, Tabatabei SS, Momen S, et al. Assessment of bone mineral density in patients undergoing hemodialysis: an Iranian population-based study. Arch Iran Med. 2021;24(8):611–8.
Nguyễn Thị Dững, Võ Tam, Loãng xương và các yếu tố nguy cơ ở bệnh nhân lọc máu định kỳ. Tạp chí Y Dược học – Trường Đại học Y Dược Huế. 2024;24:45–52.
Slouma M, Sahli H, Bahlous A, Laadhar L, Smaoui W, Rekik S, et al. Mineral bone disorder and osteoporosis in hemodialysis patients. Adv Rheumatol. 2020;60(1):26–33