Abstract
Background: Currently, a wide range of products derived from Passiflora foetida are commercially available; however, the lack of standardized extraction procedures has led to inconsistencies in product quality.
Objectives: To develop an optimized extraction process for total flavonoid content and marker compounds from Passiflora foetida using a conventional extraction method.
Materials and methods: The material studied is the leaves and stems of Passiflora foetida. The extraction conditions for vitexin, isovitexin, and total flavonoid content from Passiflora foetida were investigated and optimized using response surface methodology.
Results: The optimal extraction conditions were determined using a central composite design, with 56% ethanol concentration, a solvent-to-solid ratio of 17.54 mL/g, and a soaking time of 3 hours. Under these conditions, the extraction yields were 0.0644 ± 0.0005% for vitexin, 0.00180 ± 0.00003% for isovitexin, and 1.385 ± 0.056% for total flavonoids.
Conclusion: An optimized extraction process for bioactive compounds from P. foetida using percolation has been successfully developed.
| Published | 2025-12-30 | |
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| Issue | Vol. 15 No. 6 (2025) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2025.6.885 | |
| Keywords | Passiflora foetida, vitexin, isovitexin, flavonoid |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2025 Hue Journal of Medicine and Pharmacy
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