Nhận xét giá trị chẩn đoán của nội soi buồng tử cung và sinh thiết niêm mạc tử cung trong chẩn đoán viêm niêm mạc tử cung mạn tính

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CÁC SỐ TỪ 2011-2023
Tạp chí Y Dược Học

Abstract

Abstract:

Background: Chronic endometritis (CE) is a persistent inflammation of the endometrial lining. The prevalence of CE is high in infertile women. There is no accepted diagnostic standard. Objectives: evaluate the prevalence of CE, the characteristics of CE patients, assess the diagnostic value of CE diagnosis via hysteroscopy compared to endometrial biopsy. Methods: A prospective study was conducted on 103 patients undergoing in vitro fertilization (IVF) at Hai Phong Obstetrics and Gynecology Hospital between August 2024 and August 2025. The diagnostic criterion of biopsy for CE: ≥5 CD138+ plasma cells per 10 high-power fields (HPF); diagnostic hysteroscopy is Delphi. Results: The prevalence of CE among IVF patients was 37.8% (39/103). The most frequently hysteroscopic finding associated with CE are endometrial hyperemia (37.7%) and micropolyps (43.1%); however, these findings are not specific for CE; diffuse endometrial hyperemia was significantly higher in the CE group compared with the normal group. The diagnostic performance of hysteroscopy compared with histopathology showed a Se 85%, Sp 22%, PPV 40%, NPV 70%. The predictive ability of hysteroscopy for diagnosing CE relative to histopathological confirmation is moderate. No significant risk factors for CE were identified. Conclusion: The independent diagnostic value of hysteroscopy compared with endometrial biopsy with CD138 immunohistochemistry was moderate.

https://doi.org/10.34071/jmp.2026.3.930
Published 2026-06-28
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Issue Vol. 16 No. 3 (2026)
Section Original Articles
DOI 10.34071/jmp.2026.3.930
Keywords Keywords: Endometritis, hysteroscopy, endometrial biopsy. Từ khóa: viêm niêm mạc tử cung mạn tính, nội soi buồng tử cung, sinh thiết niêm mạc tử cung.

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Copyright (c) 2026 Hue Journal of Medicine and Pharmacy

Vũ, T. M. P., Vũ, V. T., Lưu, V. D., & Cao, N. T. (2026). Nhận xét giá trị chẩn đoán của nội soi buồng tử cung và sinh thiết niêm mạc tử cung trong chẩn đoán viêm niêm mạc tử cung mạn tính. Hue Journal of Medicine and Pharmacy, 16(3), 148–155. https://doi.org/10.34071/jmp.2026.3.930

Song D, Feng X, Zhang Q, Xia E, Xiao Y, Xie W et al. Prevalence and confounders of chronic endometritis in premenopausal women with abnormal bleeding or reproductive failure. Reproductive biomedicine online. 2018;36(1):78-83.

Yang R, Du X, Wang Y, Song X, Yang Y, Qiao J. The hysteroscopy and histological diagnosis and treatment value of chronic endometritis in recurrent implantation failure patients. Archives of gynecology and obstetrics. 2014;289:1363-9.

Kitaya KY, Tadahiro. Aberrant expression of selectin E, CXCL1, and CXCL13 in chronic endometritis. J Modern Pathology. 2010;23(8):1136-46.

Cicinelli E, Matteo M, Tinelli R, Lepera A, Alfonso R, Indraccolo U, et al. Prevalence of chronic endometritis in repeated unexplained implantation failure and the IVF success rate after antibiotic therapy. Human reproduction (Oxford, England). 2015;30(2):323-30.

Santoro A, Travaglino A, Inzani F, Angelico G, Raffone A, Maruotti GM, et al. The role of plasma cells as a marker of chronic endometritis: a systematic review and meta-analysis. Biomedicines. 2023;11(6):1714.

Cicinelli E, Vitagliano A, Kumar A, Lasmar RB, Bettocchi S, Haimovich S. Unified diagnostic criteria for chronic endometritis at fluid hysteroscopy: proposal and reliability evaluation through an international randomized-controlled observer study. Fertil Steril. 2019;112(1):162-73.e2.

Bashiri A, Halper KI, Orvieto R. Recurrent Implantation Failure-update overview on etiology, diagnosis, treatment and future directions. Reproductive Biology and Endocrinology. 2018;16(1):121.

Liu YC, Xiaoyan; Huang, Jin; Wang, Chi-Chiu;Yu, Mei-Yung et al. Comparison of the prevalence of chronic endometritis as determined by means of different diagnostic methods in women with and without reproductive failure. Fertility sterility. 2018;109(5):832-9.

Liu H, Song J, Zhang F, Li J, Kong W, Lv S, et al. A new hysteroscopic scoring system for diagnosing chronic endometritis. Journal of Minimally Invasive Gynecology. 2020;27(5):1127-32.