Pressure-supported versus t-piece spontaneous breathing trials for invasive mechanical ventilation weaning: A randomized clinical trial

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Abstract

Background: The Spontaneous Breathing Trial (SBT) is the gold standard for assessing readiness to wean from mechanical ventilation. The two most commonly used SBT techniques are the T-tube trial and pressure-supported spontaneous breathing (Pressure Support Ventilation - PSV). Objective: This study aimed to compare the success rates of passing SBT, extubation, and overall weaning between these two methods in invasively ventilated patients. Materials and Methods: A total of 133 patients eligible for SBT were randomized into two groups: the T-tube SBT group (n = 67) and the PSV-SBT group (n = 66). Evaluated variables included baseline clinical characteristics, SBT success rate, extubation success rate, and causes of weaning failure. Results: No significant differences were observed between the two groups regarding age, sex, BMI, duration of mechanical ventilation prior to SBT, Glasgow Coma Scale score, or baseline vital signs. The PSV group demonstrated a higher SBT success rate (97.0% vs. 85.1%; p < 0.05), a comparable extubation success rate (89.1% vs. 84.2%; p > 0.05), and a significantly higher overall weaning success rate (86.4% vs. 71.6%; p < 0.05) compared with the T-tube group. Conclusion: Pressure support-assisted spontaneous breathing was superior to the T-piece in achieving successful spontaneous breathing trials and ventilator weaning, suggesting it as the preferred strategy for extubation readiness in invasively ventilated patients

Keywords: Spontaneous breathing trial; pressure support; mechanical ventilation weaning; extubation.

 

 

https://doi.org/10.34071/jmp.2026.3.947
Published 2026-06-28
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Issue Vol. 16 No. 3 (2026)
Section Original Articles
DOI 10.34071/jmp.2026.3.947
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Bùi, V. D., Nguyễn, V. M., & Lê, Đức N. (2026). Pressure-supported versus t-piece spontaneous breathing trials for invasive mechanical ventilation weaning: A randomized clinical trial. Hue Journal of Medicine and Pharmacy, 16(3), 203–209. https://doi.org/10.34071/jmp.2026.3.947

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