Abstract

Objectives: 1. To determine serum complement C3, C4 concentrations in type 2 diabetes patients. 2. To investigate the relationship between serum complement C3, C4 concentrations with some clinical and subclinical characteristics. Materials and methods: A cross-sectional description study was conducted on 40 patients diagnosed with type 2 diabetes and 40 healthy individuals as the control group at Hue University of Medicine and Pharmacy Hospital from August 2022 to February 2023. Results: The mean serum C3 concentration of the patient group was 1.65 ± 0.27 g/L and was statistically significantly higher than the control group at 1.03 ± 0.19 g/L (p < 0.05). The mean serum C4 concentrations in these two groups were 0.31 ± 0.09 g/L and 0.29 ± 0.08 g/L, respectively with no statistically significant difference p > 0.05. There was a relationship between serum C3 concentration and gender, and HDL cholesterol (p < 0.05); was a positive correlation between serum C3 concentration and waist circumference and BMI (p < 0.05). There was no relationship between serum C4 levels and several other clinical and paraclinical characteristics (p > 0.05). Conclusion: Only serum C3 concentration was significantly associated with some clinical and paraclinical characteristics in type 2 diabetes patients