Tóm tắt
Bacteriocin là các polypeptide sinh học có khả năng ức chế nhiều loài vi sinh vật khác nhau. Trong tự nhiên,
nhiều loại vi khuẩn có thể sinh bacteriocin như tụ cầu coagulase âm tính (coagulase-negative Staphylococci:
CoNS). Đây là nhóm vi khuẩn thường trú phổ biến trên da và niêm mạc của con người. Chúng có khả năng sản
sinh nhiều hoạt chất kháng khuẩn như acid lactic, staphylococcin (một loại bacteriocin) tạo môi trường bất
lợi, từ đó ức chế sự phát triển của các vi sinh vật gây bệnh. Bài viết nhằm tổng hợp những vấn đề liên quan
đến bacteriocin do các vi khuẩn trong đó tập trung nhóm do CoNS tiết ra. Nhiều thành tựu gần đây trong
nghiên cứu đặc tính kháng khuẩn bacteriocin từ CoNS trong đó có staphylococcin đã mở ra tiềm năng ứng
dụng trong y học, đặc biệt là trong kiểm soát nhiễm khuẩn và thay thế kháng sinh truyền thống. Tuy nhiên,
vẫn còn nhiều thách thức cần vượt qua để hiểu rõ hơn về cơ chế hoạt động, an toàn và hiệu quả của các
bacteriocin này trước khi áp dụng rộng rãi.
| Đã xuất bản | 25-12-2025 | |
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| Số tạp chí | Tập 15 Số 7 (2025) | |
| Phân mục | Tổng quan | |
| DOI | 10.34071/jmp.2025.7.1 | |
| Từ khóa | Bacteriocin, staphylococcin, kháng khuẩn, Staphylococcus, peptide Bacteriocin, staphylococcin, Staphylococcus, peptide |
công trình này được cấp phép theo Creative Commons Attribution-phi thương mại-NoDerivatives 4.0 License International .
Bản quyền (c) 2025 Tạp chí Y Dược Huế
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