Abstract
Background: Pancreatic cancer is a highly malignant disease. Endoscopic ultrasound guided fine-needle biopsy is a novel technique for obtaining tissue samples to aid in the diagnosis of pancreatic cancer. However, its effectiveness and safety have not been extensively studied in Vietnam.
Objectives: 1. To determine the results of endoscopic guided fine needle biopsy (EUS-FNB) in patients with suspected pancreatic cancer; 2. To examine some correlations between the technical parameters and the results of EUS-FNB in patients with suspected pancreatic cancer.
Subjects and methods: Descriptive cross-sectional study on patients with suspected pancreatic cancer based on EUS-FNB specimens.
Results: A total of 81 patients were diagnosed with pancreatic cancer. EUS-FNB provided a diagnostic result on the first attempt in 92.6% of cases, on the second attempt in 6.2%, and on the third attempt in 1.2%. The overall complication rate was 4.9%, including minor bleeding along the needle puncture tract and transient abdominal pain. All complications were self-limiting and required no intervention. The mean number of needle passes was 1.69 ± 0.664. There was no significant difference in the mean number of needle passes between 19G, 20G and 22G needles (P = 0.285). There was a significant difference in suction pressure between 19G and 22G needles when obtaining standard tissue samples based on Macroscopic On-Site Evaluation (MOSE).
Conclusion: EUS-FNB achieved high diagnostic yield for pancreatic cancer most commonly after the first needle pass, with a low rate of mild, self - limited complications. There is no significant difference in the mean number of needle passes among different needle types, and suction may not be necessary when performing EUS-FNB with a 19G needle.
| Published | 2026-03-30 | |
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| Issue | Vol. 16 No. 1 (2026) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2026.1.1033 | |
| Keywords | EUS-FNB, ung thư tụy, nội soi siêu âm EUS-FNB, pancreatic cancer, Endoscopic Ultrasound |

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Copyright (c) 2026 Hue Journal of Medicine and Pharmacy
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