Abstract
Background: Sessile colorectal polyps have a significant risk of progressing to cancer and thus require effective removal. Underwater endoscopic mucosal resection (UEMR) is a novel technique that is expected to have higher efficacy and safety compared to conventional endoscopic mucosal resection (CEMR). However, effectiveness and safety of UEMR in Vietnam remains limited. This study is aimed at determining the efficacy and safety of UEMR in treating 10-20 mm sessile colorectal polyps, in compared to CEMR.
Methods: This in an observational study. 100 patients having sessile colorectal polyps (10 - 20 mm in size) at the Endoscopy Department of Cho Ray Hospital from November 2023 to June 2024 were enrolled in this study. Patients were randomly divided into two groups: UEMR (n = 50) and CEMR (n = 50).
Results: The en bloc resection rate was higher in the UEMR group than the CEMR group (100% vs. 90%, p<0.05). The negative margin (R0) rate was also superior in the UEMR group (96% vs. 84%, p<0.05). UEMR significantly reduced the rate of bleeding complications (6.0% vs. 24.0%, p<0.05) compared to CEMR. The rate of post-polypectomy electrocoagulation syndrome was lower in the UEMR group (6.0% vs. 18.0%), but the difference was not statistically significant (p>0.05).
Conclusion: UEMR is a relatively safe and effective method for treating sessile colorectal polyps 10 - 20 mm in size, achieving higher en bloc resection and R0 rates with fewer complications compared to CEMR.
| Published | 2025-06-25 | |
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| Issue | Vol. 15 No. 3 (2025) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2025.3.9 | |
| Keywords | Polyp, đại trực tràng, kỹ thuật cắt niêm mạc qua nội soi dưới nước Polyps, colorectal, underwater endoscopic mucosal resection |
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Copyright (c) 2025 Hue Journal of Medicine and Pharmacy
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