Abstract
Objective: To describe the clinical features, investigations, and treatment response of two cases of multiserosal effusions due to serosal-predominant eosinophilic gastroenteritis (EGE) managed at Nhan Dan 115 Hospital.
Methods: Case reports with detailed timelines of presentation, laboratory findings (marked peripheral eosinophilia and elevated serum IgE), low-SAAG/high-protein ascites, imaging (CT/ultrasound), endoscopy with biopsies, and outcomes after systemic corticosteroids.
Results: Both patients presented with ascites ± pleural effusions, striking eosinophilia, and high IgE, while infectious, parasitic, autoimmune, and malignant causes were excluded. Diuretics were ineffective, whereas intravenous methylprednisolone led to rapid resolution of abdominal pain/diarrhea, reduction of effusions, and normalization of eosinophil counts within one week; clinical stability was maintained at 2-week, 1- and 3-month follow-ups.
Conclusion: In patients with unexplained multiserosal effusions and peripheral eosinophilia, serosal EGE should be considered. Systemic corticosteroids are effective first-line therapy; maintenance strategies require individualization and relapse monitoring.
| Published | 2026-09-28 | |
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| Issue | Vol. 16 No. 5 (2026) | |
| Section | Case Reports | |
| DOI | 10.34071/jmp.2026.5.753 | |
| Keywords | viêm dạ dày–ruột tăng bạch cầu ái toan; eosinophilic ascites; tràn dịch đa màng; thanh mạc; corticosteroid. |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2026 Hue Journal of Medicine and Pharmacy
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