Abstract
Background: Non-invasive ventilation (NIV) has been widely applied in the management of acute respiratory failure, helping to avoid complications associated with invasive mechanical ventilation such as ventilator-associated pneumonia, prolonged hospital stay, and increased treatment costs. However, the failure rate of NIV remains high, ranging from 25% to 59%, depending on underlying conditions and disease severity.
Objective: To evaluate the predictive value of the HACOR score for NIV failure in elderly patients with acute respiratory failure. Methods: A cross-sectional descriptive study was conducted on 55 elderly patients diagnosed with acute respiratory failure who received NIV at the Intensive Care Unit from August 2024 to March 2025. The HACOR score was assessed at 1 - 3 hours, 12 hours, and 24 hours after NIV.
Results: The failure rate of elderly patients with acute respiratory failure was 36.4%. The HACOR score at 1 - 3 hours, 12 hours, 24 hours after NIV in the group of patients who failed was higher and tended to increase over time with statistical significance compared to the group that succeeded with NIV. At a cutoff value of 4.5 at 1 - 3 hours, the HACOR score predicted NIV failure with an AUROC of 0.811, sensitivity of 80%, and specificity of 88.5%. At 12 hours, a cutoff value of 5.5 yielded an AUROC of 0.878, with 63.6% sensitivity and 91.2% specificity. The HACOR score at 24 hours had limited predictive value.
Conclusion: The HACOR score is a useful tool in predicting NIV failure in elderly patients with acute respiratory failure.
| Published | 2026-01-03 | |
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| Issue | Vol. 15 No. 7 (2025) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2025.7.6 | |
| Keywords | thang điểm HACOR, TKNT không xâm nhập, suy hô hấp cấp, cao tuổi HACOR score, non-invasive ventilation, acute respiratory failure, elderly patients |
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Copyright (c) 2025 Hue Journal of Medicine and Pharmacy
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