Abstract
Background: Pancreatic cancer is one of the digestive system malignancies with the poorest prognosis. Early detection remains a significant challenge. Endoscopic ultrasound (EUS) allows for detailed evaluation of pancreatic parenchyma and can detect small tumors that may be missed by other imaging modalities.
Objectives: 1. To describe the EUS imaging features in patients with pancreatic cancer; 2. To investigate correlations between EUS findings and to compare EUS with CT scan results.
Subjects and Methods: A descriptive cross-sectional study was conducted on patients suspected of having pancreatic cancer who underwent EUS - guided fine needle biopsy (EUS - FNB).
Results: A total of 81 patients were diagnosed with pancreatic cancer, 97.5% of patients had tumor size larger than 20 mm. Most tumors appeared hypoechoic (97.5%), heterogeneous (98.8%) and had irregular margins (97.5%) on EUS. Approximately 80.2% of patients were diagnosed at an advanced stage with lymph node metastasis, vascular invasion, invasion of adjacent organs, or distant metastasis. There was a statistically significant correlation between tumor size and vascular invasion (p < 0.05). EUS and CT scan showed a moderate level of agreement in assessing lymph node staging (N stage) and vascular invasion in pancreatic cancer patients.
Conclusions: Pancreatic cancer in EUS typically presents as a hypoechoic, heterogeneous mass with irregular margins. There was a statistically significant correlation between tumor size and vascular invasion. EUS and CT scan demonstrated a moderate correlation in evaluating lymph node involvement and vascular invasion.
| Published | 2025-12-25 | |
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| Issue | Vol. 15 No. 7 (2025) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2025.7.28 | |
| Keywords | siêu âm nội soi, ung thư tụy, siêu âm nội soi và ung thư tụy EUS, Pancreatic cancer, Endoscopic Ultrasound and Pancreatic cancer |
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Copyright (c) 2025 Hue Journal of Medicine and Pharmacy
Kim NH, Kim HJ. How to optimize the diagnostic yield of endoscopic ultrasound-guided fine-needle sampling in solid pancreatic lesions from a technical perspective. International Journal of Gastrointestinal Intervention. 2023;12(2):57-63.
Marques S, Bispo M, Rio-Tinto R, Fidalgo P, Devière J. The Impact of Recent Advances in Endoscopic Ultrasound-Guided Tissue Acquisition on the Management of Pancreatic Cancer. GE Portuguese journal of gastroenterology. 2021;28(3):185-92.
Masuda S, Koizumi K, Shionoya K, Jinushi R, Makazu M, Nishino T, et al. Comprehensive review on endoscopic ultrasound-guided tissue acquisition techniques for solid pancreatic tumor. World journal of gastroenterology. 2023;29(12):1863-74.
Winter K, Talar-Wojnarowska R, Dąbrowski A, Degowska M, Durlik M, Gąsiorowska A, et al. Diagnostic and therapeutic recommendations in pancreatic ductal adenocarcinoma. Recommendations of the Working Group of the Polish Pancreatic Club. Przeglad gastroenterologiczny. 2019;14(1):1-18.
Yoshida T, Yamashita Y, Kitano M. Endoscopic Ultrasound for Early Diagnosis of Pancreatic Cancer. Diagnostics (Basel, Switzerland). 2019;9(3).
Zhang L, Sanagapalli S, Stoita A. Challenges in diagnosis of pancreatic cancer. World journal of gastroenterology. 2018;24(19):2047-60.
Rogers HK, Shah SL. Role of Endoscopic Ultrasound in Pancreatic Cancer Diagnosis and Management. Diagnostics (Basel, Switzerland). 2024;14(11).
Guo T, Xu T, Zhang S, Lai Y, Wu X, Wu D, et al. The role of EUS in diagnosing focal autoimmune pancreatitis and differentiating it from pancreatic cancer. Endoscopic ultrasound. 2021;10(4):280-7.
Kitano M, Yoshida T, Itonaga M, Tamura T, Hatamaru K, Yamashita Y. Impact of endoscopic ultrasonography on diagnosis of pancreatic cancer. Journal of gastroenterology. 2019;54(1):19-32.
Ayoub II, Talab TA, Omar H, Akoud SA, Shoreem HA, El-Deen E, et al. Impact of pancreatic head tumor size on the outcome of surgical management. The Egyptian Journal of Surgery. 2024;43(1).
Sperti C, Pasquali C, Piccoli A, Pedrazzoli S. Survival after resection for ductal adenocarcinoma of the pancreas. The British journal of surgery. 1996;83(5):62531.
Du T, Bill KA, Ford J, Barawi M, Hayward RD, Alame A, et al. The diagnosis and staging of pancreatic cancer: A comparison of endoscopic ultrasound and computed tomography with pancreas protocol. American journal of surgery. 2018;215(3):472-5.
El-Nady MA, Ead KA, Haridy MA, Shaheen N, Nashwan AJ, Abdelwahid SR, et al. Role of Endoscopic Ultrasound in Staging and Vascular Assessment of Pancreatic Cancer. Cureus. 2024;16(2):e53988.
Chatterjee A, Shah J. Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma. Diagnostics (Basel, Switzerland). 2023;14(1).
Overbeek KA, Levink IJM, Koopmann BDM, Harinck F, Konings I, Ausems M, et al. Long-term yield of pancreatic cancer surveillance in high-risk individuals. Gut. 2022;71(6):1152-60.