Abstract
Background: The study aimed to investigate the relationship between seminal oxidative stress, measured by the oxidation-reduction potential (ORP) index, and sexual function in men within infertile couples.
Materials and methods: 183 men from couples diagnosed with infertility who visited and received treatment at the Center for Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy. The patient needs to be able to obtain a semen sample thru masturbation, have complete information, and agree to participate in the study. The patient's male genitalia were examined and sexual function was assessed using the IIEF-15 scale. Semen samples were analyzed for oxidative stress results using the oxidation-reduction potential balance method.
Results: Patients with increased ORP levels in semen had a lower rate of achieving good orgasm compared to the normal ORP group (69.4% vs. 77.0%; p=0.049). Similarly, this was observed in the characteristic of overall satisfaction with sexual life (37.2% versus 50.8%; p=0.006). The ORP value is inversely correlated with the total score indicating orgasm and sexual life satisfaction. However, the correlation level is weak (-0.247 and -0.211; p=0.040 and p=0.045).
Conclusion: Seminal oxidative stress, determined by redox balance measurement, is associated with orgasm disorders and reduced overall sexual life satisfaction.
| Published | 2026-06-24 | |
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| Issue | Vol. 16 No. ONLINE FIRST (2026) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2026.5.946 | |
| Keywords | sexual dysfunction, erectile dysfunction, oxidative stress rối loạn chức năng tình dục, rối loạn cương, stress oxy hóa |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2026 Hue Journal of Medicine and Pharmacy
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